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Combinations of Bruton's tyrosine kinase inhibitors and CYP3A4 inhibitors
- 专利权人:
- Pharmacyclics LLC
- 发明人:
- Fardis, Maria,Sukbuntherng, Juthamas
- 申请号：
- AU2014244518
- 公开号：
- AU2014244518A1
- 申请日:
- 2014.03.12
- 申请国别(地区):
- AU
- 年份:
- 2015
- 代理人:
- 摘要：
- Combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-3-(4- phenoxyphenyl)- 1 H-pyrazolo [3,4-d]pyrimidin- 1 -yl)piperidin- 1 -yl)prop-2-en- 1 -one, with CYP3A4 inhibitors are provided. Also provided are methods of treating cancers, and autoimmune disorders by administering combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1 H-pyrazolo [3, 4-d]pyrimidin-l - yl)piperidin-l-yl)prop-2-en-1-one, and CYP3A4 inhibitors.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
