COMBINATIONS OF BRUTONS TYROSINE KINASE INHIBITORS AND CYP3A4 INHIBITORS

• 收藏
• 分享

专利权人:

PHARMACYCLICS LLC

发明人:

FARDIS, Maria,SUKBUNTHERNG, Juthamas

申请号：

HK16107733.9

公开号：

HK1224173A

申请日:

2016.07.04

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

Combinations of Brutons tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, with CYP3A4 inhibitors are provided. Also provided are methods of treating cancers, and autoimmune disorders by administering combinations of Brutons tyrosine kinase (Btk) inhibitors, e.g., 1-4((R)-3-(4-amino-3-(4-phenoxyphenyl)-1 H-pyrazolo[3, 4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, and CYP3A4 inhibitors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/