Zoltan Zubovics;John Bruce Patterson;Zhipeng Wu;Andras Toro;Qingping Zeng;Warren Stanfield Wade;Yun Yang
发明人:
Qingping Zeng,Andras Toro,John Bruce Patterson,Warren Stanfield Wade,Zoltan Zubovics,Yun Yang,Zhipeng Wu
申请号：
US13639734
公开号：
US09040714B2
申请日:
2011.04.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts there-of. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.
