Qingping ZENG,Andras TORO,John Bruce PATTERSON,Warren Stanfield WADE,Zoltan ZUBOVICS,Yun YANG,Zhipeng WU
申请号：
US16429460
公开号：
US20190314330A1
申请日:
2019.06.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.
