Qingping Zeng,Andras Toro,John Bruce Patterson,Warren Stanfield Wade,Zoltan Zubovics,Yun Yang,Zhipeng Wu
申请号：
US15836728
公开号：
US20180228765A1
申请日:
2017.12.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.
