Qingping Zeng,Andras Toro,John Bruce Patterson,Warren Stanfield Wade,Zoltan Zubovics,Yun Yang,Zhipeng Wu
申请号：
US14594400
公开号：
US09693992B2
申请日:
2015.01.12
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.
