Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1

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专利权人:

Frank Himmelsbach

发明人:

Frank Himmelsbach

申请号：

US13646031

公开号：

US08629138B2

申请日:

2012.10.05

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Disclosed is a compound represented by Formula (Im1):or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Also disclosed are pharmaceutical compositions comprising the compound of Formula (Im1) or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof and methods of inhibiting 11β-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formula (Im1), or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Values for the variables in Formula (Im1) are defined herein.

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