Colin M. Tice;Yuanjie Ye;Katerina Leftheris;Wei Zhao;Linghang Zhuang;Suresh B. Singh;David A. Claremon
发明人:
David A. Claremon,Katerina Leftheris,Suresh B. Singh,Colin M. Tice,Yuanjie Ye,Wei Zhao,Linghang Zhuang
申请号:
US13381123
公开号:
US08883778B2
申请日:
2010.06.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are compounds represented by Formula (I):or pharmaceutically acceptable salts, enantiomers or diastereomers thereof. Also disclosed are pharmaceutical compositions comprising the compounds of Formula (I) or pharmaceutically acceptable salts, enantiomers or diastereomers thereof for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. Values for the variables of Formula (I) are defined herein.