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Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
专利权人:
Colin M. Tice;Yuanjie Ye;Katerina Leftheris;Wei Zhao;Zhenrong Xu;Salvacion Cacatian;Linghang Zhuang;Suresh B. Singh;David A. Claremon
发明人:
David A. Claremon,Linghang Zhuang,Katerina Leftheris,Colin M. Tice,Zhenrong Xu,Yuanjie Ye,Suresh B. Singh,Salvacion Cacatian,Wei Zhao
申请号:
US12741522
公开号:
US08138178B2
申请日:
2009.04.30
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed is a compound represented by Formula (Im1)or a pharmaceutically acceptable salt, enantiomer or diastereomer thereof. Also disclosed are pharmaceutical compositions comprising the compound of Formula (Im1) or a pharmaceutically acceptable salt, enantiomer or diastereomer thereof and methods of inhibiting 11β-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formulas (Im1), or a pharmaceutically acceptable salt, enantiomer or diastereomer thereof.
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