Colin M. Tice;Yuanjie Ye;Wei He;Wei Zhao;Zhenrong Xu;Salvacion Cacatian;Linghang Zhuang;Suresh B. Singh;David A. Claremon
发明人:
David A. Claremon,Linghang Zhuang,Colin M. Tice,Yuanjie Ye,Wei He,Suresh B. Singh,Zhenrong Xu,Salvacion Cacatian,Wei Zhao
申请号：
US12747391
公开号：
US08440658B2
申请日:
2008.12.10
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed is a compound represented by Formula (I):or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Also disclosed are pharmaceutical compositions comprising the compound of Formula (I) or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof and methods of inhibiting 11β-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Values for the variables in Formula (I) are defined herein.
