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PROCESSES FOR PREPARING MEDICAMENTS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND INTERMEDIATES FOR USE THEREIN
专利权人:
发明人:
RUSSO DOMENICO,WAHNON JORGE,MATON WILLIAM,WEBER BEAT T,JERNIMO PAULA,SOUSA LUSA,BARROCAS PEDRO,PIRES RITA,LIMA RICARDO,VASCONCELOS TE³FILO
申请号:
IN201617008228
公开号:
IN201617008228A
申请日:
2016.03.09
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides a compound of formula N wherein: X is CH2, oxygen or sulphur; Ri, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkyloxy, hydroxy, nitro, alkylcarbonylamino, alkylamino or dialkylamino group, wherein N is in the form of the individual R- and S-enantiomer or a mixture of the (R)- and (S)-enantiomer. The present invention also provides a compound of formula MA. The present invention also provides processes for preparing the above compounds, and processes involving their use. The compounds are particularly useful as intermediates in the synthesis of peripherally-selective inhibitors of dopamine-B-hydroxylase.
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