The invention relates to biology and to human and animal physiology. The inventive method for optimising functional status of vegetative systems of the human organism consists in exposing the biologically active areas of the human body to the action of microwave electromagnetic pulse by exposing each area to the radiation, the frequency of which is predetermined separately for each area or for several areas equivalent in linear dimensions, the constant mean energy-flux density of which is maintained during the entire session, which is amplitude modulated by a signal which is quasi-randomly variable in the range of 20 Hz-50kHz and which is circularly polarized.; The inventive device for carrying out said method comprises, in-series connected, a microwave frequency generator, a modulator in the form of a pulse generator of quasi-random signals, a radiating aerial in the form of a flat broadside array and a control unit connected to each above-listed units. The aerial is embodied in such a way that it is circularly polarized and the device is also provided with a dielectric spacer, the thickness of which is fixed, which is made of a material transparent for the operating bandwidth and which is placeable between the aerial and the radiation area.