Kristen J. Hansen;Joan T. Moseman;Peter R. Johnson;Amy S. Determan;Ryan T. Woldt
发明人:
Amy S. Determan,Peter R. Johnson,Joan T. Moseman,Ryan T. Woldt,Kristen J. Hansen
申请号:
US13699805
公开号:
US09693950B2
申请日:
2011.05.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Aqueous formulations that include at least one active pharmaceutical ingredient; and at least one excipient, wherein the aqueous formulation has a viscosity of from 500 to 30,000 centipoise when measured at a shear rate of 100 s−1 and a temperature of 25° C.; a surface tension that is not greater than 60 dynes/cm when measured under ambient conditions; or a contact angle on a medical grade polymeric material of 50° or greater when measured under ambient conditions. Methods of coating and coated microneedle arrays using the aqueous formulations are also disclosed herein.