Multivalent immunogenic composition comprising 13 (capsular polysaccharide of different Serotype of Streptococcus pneumoniae Protein along with a vehicle and acceptable method for InduCir an immune response to a polysaccharide conjugate (Divisional Sun. No 566 - 16).
HAUSDORFF WILLIAM P.,SIBER GEORGE RAINER,PARADISO PETER R.
申请号：
CL2017002206
公开号：
CL2017002206A1
申请日:
2017.08.31
申请国别(地区):
CL
年份:
2018
代理人:
摘要：
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection.COMPOSICIÓN INMUNOGÉNICA MULTIVALENTE QUE COMPRENDE 13 CONJUGADOS POLISACARIDO CAPSULAR DE UN SEROTIPO DIFERENTE DE STREPTOCOCCUS PNEUMONIAE-PROTEÍNA JUNTO CON UN VEHÍCULO ACEPTABLE Y MÉTODO PARA INDUCIR UNA RESPUESTA INMUNE A UN CONJUGADO DE POLISACARIDO (DIVISIONAL DE SOL. N° 566-16).
