multivalent immunogenic composition, and pharmaceutical composition for inducing an immune response to a streptococcus pneumoniae capsular polysaccharide conjugate
DONG-SOO HAM,HUN KIM,JI-HYE YANG,JIN-HWAN SHIN,MAHN-HOON PARK,MYEONG-JU NOH,SEON-YOUNG YANG,SU-JIN PARK
申请号：
BR112014032091
公开号：
BR112014032091A2
申请日:
2013.06.19
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Provided is an immunogenic composition comprising 15 different polysaccharide-protein conjugates. Each of the conjugates comprises a capsular polysaccharide prepared from different serotype Streptococcus pneumoniae conjugated to a carrier protein, that is, serotypes 1, 2, 3, 4, 5, 6A, 6B, 7F, 9N, 9V, 14, 18C, 19A, 19F and 23F. An immunogenic composition formulated into a vaccine comprising an aluminum-based adjuvant increases application range with respect to pneumococcal diseases in infants and children.
