BIEMANS, RALPH LEON,DUVIVIER, PIERRE,GAVARD, OLLIVIER FRANCIS NICOLAS,POOLMAN, JAN
申请号：
SG2012062733
公开号：
SG183475A1
申请日:
2010.08.17
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
The present invention relates to an immunogenic composition comprising at least 2 different S. pneumoniae capsular saccharides, wherein one or more is/are selected from a first group consisting of serotypes 1, 3, 19A and 19F which is/are linked to a protein carrier(s) either directly or indirectly through a chemistry other than reductive amination, and one or more different saccharides is/are selected from a second group consisting of serotypes 4, 5, 6A, 6B, 7F, 9V, 14, 18C and 23F which is/are linked to a protein carrier(s) by reductive amination. Uses of such compositiosn in the treatment or prevention of diseases caused by Streptococcus pneumoniae infection are also disclosed.
