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Immunogenic composition comprising S. pneumoniae polysaccharides conjugated to carrier proteins
专利权人:
GlaxoSmithKline Biologicals s.a.
发明人:
Biemans, Ralph Leon,Duvivier, Pierre,Gavard, Ollivier Francis Nicolas,Poolman, Jan
申请号:
AU2010348155
公开号:
AU2010348155B2
申请日:
2010.08.17
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to an immunogenic composition comprising at least 2 different S. pneumoniae capsular saccharides, wherein one or more is/are selected from a first group consisting of serotypes 1, 3, 19A and 19F which is/are linked to a protein carrier(s) either directly or indirectly through a chemistry other than reductive amination, and one or more different saccharides is/are selected from a second group consisting of serotypes 4, 5, 6A, 6B, 7F, 9V, 14, 18C and 23F which is/are linked to a protein carrier(s) by reductive amination. Uses of such compositiosn in the treatment or prevention of diseases caused by Streptococcus pneumoniae infection are also disclosed.
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