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IMMUNOGENIC COMPOSITION COMPRISING S. PNEUMONIAE POLYSACCHARIDES CONJUGATED TO CARRIER PROTEINS
专利权人:
发明人:
BIEMANS RALPH LEON,DUVIVIER PIERRE,GAVARD OLLIVIER FRANCIS NICOLAS,POOLMAN JAN
申请号:
IN2369/KOLNP/2012
公开号:
IN2012KN02369A
申请日:
2012.08.24
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention relates to an immunogenic composition comprising at least 2 different S. pneumoniae capsular saccharides, wherein one or more is/are selected from a first group consisting of serotypes 1,3,19A and 19F which is/are linked to a protein carrier(s) either directly or indirectly through a chemistry other than reductive amination and one or more different saccharides is/are selected from a second group consisting of serotypes 4,5,6A,6B,7F,9V,14,18C and 23F which is/are linked to a protein carrier(s) by reductive amination. Uses of such compositiosn in the treatment or prevention of diseases caused by Streptococcus pneumoniae infection are also disclosed.
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