President and Fellows of Harvard College;哈佛大學的校長及成員們
发明人:
MYERS, Andrew G.,SEIPLE, Ian Bass,ZHANG, Ziyang,I．B．賽普勒,ZHANG, Ziyang,Z．張
申请号：
HK18102636.6
公开号：
HK1242920A
申请日:
2018.02.23
申请国别(地区):
HK
年份:
2018
代理人:
摘要：
Provided herein are methods of preparing new 14-membered ketolides via coupling of an eastern and western half moiety, followed by macro-cyclization, and optional functionalization. Intermediates in the synthesis of these ketolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using these ketolides are also provided.
