KETOLIDES A 14 CHAINONS ET LEURS PROCEDES DE PREPARATION ET D'UTILISATION

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专利权人:

PRESIDENT AND FELLOWS OF HARVARD COLLEGE

发明人:

MYERS, ANDREW G.,SEIPLE, IAN BASS,ZHANG, ZIYANG

申请号：

CA2963815

公开号：

CA2963815A1

申请日:

2015.10.08

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Provided herein are methods of preparing new 14-membered ketolides via coupling of an eastern and western half moiety, followed by macrocyclization, and optional functionalization. Intermediates in the synthesis of these ketolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using these ketolides are also provided.

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中国工程科技知识中心

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http://www.ckcest.cn/home/