BIRKETT, Stephen, Lonsdale,DONOHUE, Andrew, Craig,D'SOUZA, Asha, Marina,NG, Sara, Man Yee,SULISTIO, Adrian,TAIT, Russell, John,VALADE, David,NAYLOR, Alan
申请号：
HK19100926
公开号：
HK1258571A1
申请日:
2019.01.18
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.
