DONOHUE Andrew Craig;D'SOUZA Asha Marina;TAIT Russell John;VALADE David;POLYACTIVA PTY LTD;BIRKETT Stephen Lonsdale;NAYLOR Alan;NG Sara Man Yee;SULISTIO Adrian
发明人:
BIRKETT Stephen Lonsdale,DONOHUE Andrew Craig,D'SOUZA Asha Marina,NG Sara Man Yee,SULISTIO Adrian,TAIT Russell John,VALADE David,NAYLOR Alan,DSOUZA Asha Marina
申请号:
IL25791118
公开号:
IL257911D0
申请日:
2018.03.06
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.