Birkett, Stephen Lonsdale,Donohue, Andrew Craig,D'Souza, Asha Marina,Ng, Sara Man Yee,Sulistio, Adrian,Tait, Russell John,Valade, David,Naylor, Alan,DSouza, Asha Marina
申请号：
AU2016318344
公开号：
AU2016318344A1
申请日:
2016.09.09
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.
