BIRKETT, STEPHEN LONSDALE,DONOHUE, ANDREW CRAIG,D'SOUZA, ASHA MARINA,NG, SARA MAN YEE,SULISTIO, ADRIAN,TAIT, RUSSELL JOHN,VALADE, DAVID,NAYLOR, ALAN,BLENCOWE, ANTON,DSOUZA, ASHA MARINA
申请号：
CA2997519
公开号：
CA2997519A1
申请日:
2016.09.09
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.
