DILUZIO WILLOW,TRUONG NOBEL T,VARGA CSANAD M,PALANIAPPAN VAITHIANATHAN,BROWN JASON
申请号：
CO13259825
公开号：
CO6801647A2
申请日:
2013.11.01
申请国别(地区):
CO
年份:
2013
代理人:
摘要：
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-&alpha4&bgr7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-&alpha4&bgr7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-&alpha4&bgr7 antibody in vivo.
