DILUZIO, Willow,TRUONG, Nobel T.,PALANIAPPAN, Vaithianathan,BROWN, Jason,FOX, Irving H.,SCHOLZ, Catherine,VARGA, Csanad M.
申请号：
DK12721093
公开号：
DK2704798T3
申请日:
2012.05.02
申请国别(地区):
DK
年份:
2017
代理人:
摘要：
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-±4²7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-±4²7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-±4²7 antibody in vivo.
