DILUZIO Willow,DILUZIO Willow,TRUONG Nobel T.,TRUONG Nobel T.,VARGA Csanad M.,VARGA Csanad M.,PALANIAPPAN Vaithianathan,PALANIAPPAN Vaithianathan,BROWN Jason,BROWN Jason,FOX Irving H.,FOX Irving H.,SC
申请号：
SI201231073
公开号：
SI2704798T1
申请日:
2012.05.02
申请国别(地区):
SI
年份:
2017
代理人:
摘要：
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-±4²7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-±4²7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-±4²7 antibody in vivo.
