VAITHIANATHAN PALANIAPPAN,NOBEL T. TRUONG,CSANAD M. VARGA,WILLOW DILUZIO,JASON BROWN,IRVING H. FOX,CATHERINE SCHOLZ
申请号：
PT12721093
公开号：
PT2704798T
申请日:
2012.05.02
申请国别(地区):
PT
年份:
2017
代理人:
摘要：
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-&alpha4&bgr7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-&alpha4&bgr7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-&alpha4&bgr7 antibody in vivo.
