#$%^&*AU2016100366A420160512.pdf#####ABSTRACT The present invention provides a method of isolating at least one ingredient in particular an ingredient with anti-viral efficacy selected from the group consisting of an alkaloid, a triterpenoid, a lignan, a phenylethanoid, a sesquiterpene lactone and a flavonoid from Baphicacanthus cusia. The method can be used to isolate and obtain for example about 30 ingredients. Among them are two new alkaloids which have not been previously reported. Moreover, the method allows for isolating 12 compounds which could not or have not been isolated so far, i.e. which can be isolated for the first time with the method of the present invention. Experimental tests confirmed an exceptional anti-viral efficacy of ingredients isolated. The present invention further refers to a composition, in particular a pharmaceutical composition comprising the at least one ingredient and at least one pharmaceutical tolerable excipient. Still further, the present invention refers to a method of treating a subject suffering from a viral disease by administering at least one ingredient isolated from Baphicacanthus cusia. In accordance with the invention, a method of treating a subject suffering from a viral disease by administering at least one compound having certain formula to the subject is provided, too. 47
