Theodore Randolph,Robert Garcea,Kimberly J. Hassett
申请号：
US15309169
公开号：
US20170065707A1
申请日:
2015.05.06
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Embodiments of the present invention provide for novel compositions and methods for making and using a thermally stable human papilloma virus (HPV) formulation or other stabilized multimeric virus formulation. Certain embodiments concern lyophilizing HPV formulations in the presence or absence of adjuvants. Other embodiments concern lypophilizing HPV capsomere vaccines in order to increase stability of an immunogenic composition against HPV infection for storage, delivery and use. In yet other embodiments, a single immunogenic composition can include a thermally stable formulation of multiple virus serotypes.
