The present invention provides a dermatological adhesive composition having an enhanced skin protective effect. The present invention provides a dermatological adhesive composition comprising a resin component for forming an adhesive and a lamellar structure formed of a lipid composition; a dermatological adhesive composition comprising a resin component for forming an adhesive, and a lipid composition containing at least one selected from the group consisting of sphingolipids and sterols and at least one selected from the group consisting of higher alcohols and surfactants; and a dermatological patch including a base sheet, and an adhesive layer formed of the dermatological adhesive composition and disposed on the base sheet.