A palladium-copper catalyst of homogeneous selective oxidation of thiols is proposed, combining a functional binuclear thiolate-bridged coordination compound of palladium (II) and a modifying thiolate complex of copper (I), having the general formula [Pd2II(µ-SR)2(NH3)4] · {CuIk(SR)m} (I),whereSR is the residue of a thiolate ligand, chosen from the group including a residue of glutathione and acetylcysteine,k = 2 to 14,m ≥ 3k.Also proposed are a catalytic combination, a pharmacological combination, a pharmaceutical composition, and a method of therapeutic action on a patients organism based on the indicated catalyst.