BALAZOVSKY, MARK BORISOVICH,ANTONOV, VIKTOR GEORGIEVICH,BELYAEV, ALEXANDR NIKOLAEVICH,EREMIN, ALEXEI VLADIMIROVICH
申请号：
EP11855523
公开号：
EP2664614A4
申请日:
2011.12.30
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
A palladium-copper catalyst of homogeneous selective oxidation of thiols is proposed, combining a functional binuclear thiolate-bridged coordination compound of palladium (II) and a modifying thiolate complex of copper (I), having the general formula [Pd2II(µ-SR)2(NH3)4] · {CuIk(SR)m} (I),whereSR is the residue of a thiolate ligand, chosen from the group including a residue of glutathione and acetylcysteine,k = 2 to 14,m ≥ 3k.Also proposed are a catalytic combination, a pharmacological combination, a pharmaceutical composition, and a method of therapeutic action on a patients organism based on the indicated catalyst.
