Mark Borisovich Balazovsky,Viktor Georgievich Antonov,Alexandr Nikolaevich Belyaev,Alexei Vladimirovich Eremin
申请号:
US13978936
公开号:
US20130289108A1
申请日:
2011.12.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A palladium-copper catalyst of homogeneous selective oxidation of thiols is proposed, combining a functional binuclear thiolate-bridged coordination compound of palladium (II) and a modifying thiolate complex of copper (I), having the general formula[Pd2II(μ-SR)2(NH3)4]·{CukI(SR)m} (I),whereSR is the residue of a thiolate ligand, chosen from the group including a residue of glutathione and acetylcysteine,k=2 to 14,m≧3k.Also proposed are a catalytic combination, a pharmacological combination, a pharmaceutical composition, and a method of therapeutic action on a patients organism based on the indicated catalyst.