Composition and method for treating and/or preventing biological contamination using a biocide composition comprising at least one quaternary ammonium compound and urea. The method includes drying urea, and thereafter combining at least one quaternary ammonium compound and urea and may produce a potent biocide composition that is stable and able to chemically treat biological contamination in a variety of difficult to reach locations. Uses of the composition are also described.一種使用含有至少一種四級銨化合物與尿素的殺生物劑組成物來處理及/或預防生物污染之組成物與方法。該方法包括乾燥尿素,然後混合至少一種四級銨化合物與尿素,且可以製造安定並能化學處理種種難以抵達位置之生物污染的強效殺生物劑組成物。本發明亦描述該組成物之用途。