BURY, MICHAEL JONATHAN,CASILLAS, LINDA N.,CHARNLEY, ADAM KENNETH,DEMARTINO, MICHAEL P.,DONG, XIAOYANG,EIDAM, PATRICK M.,HAILE, PAMELA A.,MARQUIS, JR., ROBERT W.,RAMANJULU, JOSHI M.,ROMANO, JOSEPH J.,S
申请号：
PE2014000212
公开号：
PE20141408A1
申请日:
2012.08.17
申请国别(地区):
PE
年份:
2014
代理人:
摘要：
It refers to a formula compound, wherein R1 is h, SO2 is tar (C1-C4),-Combined asphalt (C1-C4) or asphalt (C1-C4)；R2 is - MS, Sora, so2ra, so2nh2, RA is asphalt (C1-C6), among others,1. Halogen asphalt (C1-C6),Bicycle (C3-C7),R3 is, among other things, h, halogen, hydroxy, hydrocarbyl (C1-4),Alquenilo（C2-C4），Z is, among other things, phenyl or pyridine. They are the preferred compounds: n-1,3-benzodiazo-5-il-6 - [(1,1-dimethyl) sulfur] - 4-quinine； 2 - ((4 - ((4,5-dimethyl-1h-pirazol-3-il) amine) - 7-methoxynitrous-6-il) sulfuric acid； and so on. He also mentioned a composer of pharmacologySE REFIERE A COMPUESTOS DE FORMULA (I) DONDE: R1 ES H, -SO2-ALQUILO(C1-C4), -CO-ALQUILO (C1-C4) O ALQUILO (C1-C4)； R2 ES -SRa, -SORa, -SO2Ra, -SO2NH2, ENTRE OTROS, EN DONDE Ra ES ALQUILO(C1-C6), HALO-ALQUILO(C1-C6), CICLOALQUILO (C3-C7), ENTRE OTROS； R3 ES H, HALOGENO, HIDROXI, ALQUILO (C1-4), ALQUENILO (C2-C4), ENTRE OTROS； Z ES FENILO O PIRIDILO. SON COMPUESTOS PREFERIDOS: N-1,3-BENZOTIAZOL-5-IL-6-[(1,1-DIMETILETIL)SULFONIL]-4-QUINAZOLINAMINA； 2-((4-((4,5-DIMETIL-1H-PIRAZOL-3-IL)AMINO)-7-METOXIQUINAZOLIN-6-IL)SULFONIL)ETANOL； ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA
