Refers to a compound of formula I, wherein R1 is H, c1-c4 alkyl R2 is c1-c6 alkyl, cycloalkyl alquenilo C2 - C3 - C7, C4, among others R3 is H or next to or Form l-alaninate lysyl -, L - L - L - alaninate, ornitinato, among others.Preferred compounds are: 2 - {[2 - (4-chlorophenyl) - 1,3 - thiazol-4-yl] methyl} sulfanyl) - 4 - [4 - (2-hydroxyethoxy) phenyl] - 6 - (pyrrolidin-1-yl) pyridin - 3.5 - dicarbonitrilo hydrochloride L - alalnil - l-alaninate 2 - {[2 - (4 - [2 - (4-chlorophenyl) - 1,3 - thiazol-4-yl] methyl} - 3.5 - diciano sulfanyl) - 6 - (pyrrolidin-1-yl) pyridin-4-yl Phenoxy] ethyl} among others.These compounds are useful in the prophylaxis and \/ or treatment of diabetes, dyslipidemia and metabolic syndromeREFERIDA A UN COMPUESTO DE FORMULA I, DONDE R1 ES H, ALQUILO C1-C4 R2 ES ALQUILO C1-C6, ALQUENILO C2-C4, CICLOALQUILO C3-C7, ENTRE OTROS R3 ES H O JUNTO AL O FORMAN L-ALANINATO, L-LISIL-L-ALANINATO, L-ORNITINATO, ENTRE OTROS.SON COMPUESTOS PREFERIDOS: 2-({[2-(4-CLOROFENIL)-1,3-TIAZOL-4-IL]METIL}SULFANIL)-4-[4-(2-HIDROXIETOXI)FENIL]-6-(PIRROLIDIN-1-IL)PIRIDIN-3,5-DICARBONITRILO CLORHIDRATO DE L-ALALNIL-L-ALANINATO DE 2-{4-[2-({[2-(4-CLOROFENIL)-1,3-TIAZOL-4-IL]METIL}SULFANIL)-3,5-DICIANO-6-(PIRROLIDIN-1-IL)PIRIDIN-4-IL]FENOXI}ETILO ENTRE OTROS. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO Y/O PROFILAXIS DE DIABETES, SINDROME METABOLICO Y DISLIPIDEMIAS
