The present disclosure relates to triazolopyrimidine derivatives, preparation processes and pharmaceutical use thereof. Specifically, the present disclosure relates to triazolopyrimidine derivatives presented by formula (I), and their use as therapeutic agents, especially use as P2Y12 receptor agonists, wherein each substitute group of general formula (I) is as defined in the specification.本發明涉及三唑並嘧啶類衍生物、其製備方法及其用途。具體而言,本發明涉及一種通式(I)所示的三唑並嘧啶類衍生物,以及它們作為治療劑特別是作為P2Y12受體拮抗劑的用途,其中通式(I)中的各取代基的定義與說明書中的定義相同。