The present disclosure relates to heteroaryl-pyrimidine derivatives, preparation processes and pharmaceutical use thereof. Specifically, the present disclosure relates to heteroaryl-pyrimidine derivatives presented by formula (I) and pharmaceutically acceptable salts thereof, and their use as a cancer therapeutic agent, especially use as a mTOR inhibitor, wherein each substitute group of general formula (I) is as defined in the specification.本發明涉及雜芳基並嘧啶類衍生物、其製備方法和用途。具體而言,本發明涉及一種通式(I)所示雜芳基並嘧啶類衍生物及其可藥用鹽,以及它們作為癌症治療劑特別是作為mTOR抑制劑的用途,其中通式(I)中的各取代基的定義與說明書中的定義相同。
