PHARMACEUTICAL COMPOSITION TO PROTECT AN ANIMAL AGAINST A DISORDER ARISING FROM AN INFECTION WITH A BACTERIUM THAT BELONGS TO THE GROUP OF NOCARDIOFORM ACTINOMYCETES
JACOBS, ANTONIUS ARNOLDUS CHRISTIAAN,VAN DER GEIZE, ROBERT,DIJKHUIZEN, LUBBERT
申请号:
NZ59358810
公开号:
NZ593588A
申请日:
2010.01.11
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a pharmaceutical composition adapted to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes having the ability to survive within macrophages of the animal, comprising live bacteria of a nocardioform actinomycetes species, the live bacteria being attenuated by inactivation of a gene that encodes a protein involved in methylhexahydroindanedione propionate degradation, and a pharmaceutically acceptable carrier for these live bacteria.