Pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes
Antonius Arnoldus Christiaan Jacobs,Robert Van Der Geize,Lubbert Dijkhuizen
申请号：
US13144042
公开号：
US08574565B2
申请日:
2010.01.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention pertains to a pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes having the ability to survive within macrophages of the animal, comprising live bacteria of a nocardioform actinomycetes species, the live bacteria being attenuated by inactivation of a gene that encodes a protein involved in methylhexahydroindanedione propionate degradation, and a pharmaceutically acceptable carrier for these live bacteria.
