PHARMACEUTICAL COMPOSITION TO PROTECT AN ANIMAL AGAINST A DISORDER ARISING FROM AN INFECTION WITH A BACTERIUM THAT BELONGS TO THE GROUP OF NOCARDIOFORM ACTINOMYCETES
JACOBS, ANTONIUS ARNOLDUS CHRISTIAAN,VAN DER GEIZE, ROBERT,DIJKHUIZEN, LUBBERT
申请号：
CA2749075
公开号：
CA2749075C
申请日:
2010.01.11
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention pertains to a pharmaceutical composition to protect an animalagainst a disorder arising from an infectionwith a bacterium that belongs to the group of nocardioform actinomyceteshaving the ability to survive withinmacrophages of the animal, comprising live bacteria of a nocardioformactinomycetes species, the live bacteria being attenuatedby inactivation of a gene that encodes a protein involved inmethylhexahydroindanedione propionate degradation, and apharmaceutically acceptable carrier for these live bacteria.
