Pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes
Jacobs, Antonius Arnoldus Christiaan,Van Der Geize, Robert,Dijkhuizen, Lubbert
申请号:
AU2010204269
公开号:
AU2010204269B2
申请日:
2010.01.11
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The invention pertains to a pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes having the ability to survive within macrophages of the animal, comprising live bacteria of a nocardioform actinomycetes species, the live bacteria being attenuated by inactivation of a gene that encodes a protein involved in methylhexahydroindanedione propionate degradation, and a pharmaceutically acceptable carrier for these live bacteria.