Tracy Chia-Chien KUO,Bijan Andre BOLDAJIPOUR,Javier Fernando CHAPARRO RIGGERS,Philippe DUCHATEAU,Roman Ariel GALETTO,Alexandre JUILLERAT,Thomas Charles PERTEL,Arvind RAJPAL,Barbra Johnson SASU,Cesar A
申请号：
US16384719
公开号：
US20190241669A1
申请日:
2019.04.15
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention provides CARs (CARs) that specifically bind to BCMA (B-Cell Maturation Antigen). The invention further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and methods of making such CARs, engineered immune cells, and nucleic acids. The invention further relates to therapeutic methods for use of these CARs and engineered immune cells for the treatment of a condition associated with malignant cells expressing BCMA (e.g., cancer).
