KUO TRACY CHIA CHIEN,CHAPARRO RIGGERS JAVIER FERNANDO,SASU BARBRA JOHNSON,GALETTO ROMAN,BOLDAJIPOUR BIJAN ANDRE,SOMMER CESAR ADOLFO,VAN BLARCOM THOMAS JOHN,PERTEL THOMAS CHARLES,RAJPAL ARVIND,DUCHATEA
申请号：
IN201717039288
公开号：
IN201717039288A
申请日:
2017.11.03
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The invention provides Chimeric Antigen Receptors (CARs) that specifically bind to BCMA (B-Cell Maturation Antigen). The invention further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and methods of making such CARs, engineered immune cells, and nucleic acids. The invention further relates to therapeutic methods for use of these CARs and engineered immune cells for the treatment of a condition associated with malignant cells expressing BCMA (e.g., cancer).
