KUO, Tracy Chia-Chien,CHAPARRO RIGGERS, Javier Fernando,SASU, Barbra Johnson,GALETTO, Roman,BOLDAJIPOUR, Bijan Andre,SOMMER, Cesar Adolfo,VAN BLARCOM, Thomas John,PERTEL, Thomas Charles,RAJPAL, Arvind
申请号：
SG11201707089W
公开号：
SG11201707089WA
申请日:
2016.03.30
申请国别(地区):
SG
年份:
2017
代理人:
摘要：
The invention provides CARs (CARs) that specifically bind to BCMA (B-Cell Maturation Antigen). The invention further relates to engineered immune cells comprising such CARs, CAR-encoding nucleic acids, and methods of making such CARs, engineered immune cells, and nucleic acids. The invention further relates to therapeutic methods for use of these CARs and engineered immune cells for the treatment of a condition associated with malignant cells expressing BCMA (e.g., cancer).
