Zebala, John A.,Maeda, Dean Y.,Morgan, Joel R.,Kahn, Stuart J.
申请号:
AU2010206631
公开号:
AU2010206631B2
申请日:
2010.01.23
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
There is disclosed a pharmaceutical composition comprising racemic aminopterin or pharmaceutically acceptable salts thereof. There is further disclosed a method to treat a disorder in a patient comprising administering a therapeutically effective amount of racemic aminopterin or pharmaceutically acceptable salts of racemic aminopterin. More particularly, there is disclosed a method for treating disorders modulated by at least dihydrofolate reductase activity, such as cancers and inflammatory disorders, wherein the method comprises administering to a patient in need thereof a therapeutically effective amount of racemic aminopterin or a pharmaceutically acceptable salt thereof.