John A Zebala,Dean Y Maeda,Joel R Morgan,Stuart J Kahn
申请号:
IN1515/MUMNP/2011
公开号:
IN2011MN01515A
申请日:
2011.07.20
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
There is disclosed a pharmaceutical composition comprising racemic aminopterin or pharmaceutically acceptable salts thereof. There is further disclosed a method to treat a disorder in a patient comprising administering a therapeutically effective amount of racemic aminopterin or pharmaceutically acceptable salts of racemic aminopterin. More particularly, there is disclosed a method for treating disorders modulated by at least dihydrofolate reductase activity, such as cancers and inflammatory disorders, wherein the method comprises administering to a patient in need thereof a therapeutically effective amount of racemic aminopterin or a pharmaceutically acceptable salt thereof.