Dean Y. Maeda;Joel R. Morgan;Stuart J. Kahn;John A. Zebala
发明人:
John A. Zebala,Dean Y. Maeda,Joel R. Morgan,Stuart J. Kahn
申请号：
US12692593
公开号：
US08349837B2
申请日:
2010.01.23
申请国别(地区):
US
年份:
2013
代理人:
摘要：
There is disclosed a pharmaceutical composition comprising racemic aminopterin or pharmaceutically acceptable salts thereof. There is further disclosed a method to treat a disorder in a patient comprising administering a therapeutically effective amount of racemic aminopterin or pharmaceutically acceptable salts of racemic aminopterin. More particularly, there is disclosed a method for treating disorders modulated by at least dihydrofolate reductase activity, such as cancers and inflammatory disorders, wherein the method comprises administering to a patient in need thereof a therapeutically effective amount of racemic aminopterin or a pharmaceutically acceptable salt thereof.
