Pandey, Anjali,Venkataramani, Chandrasekar,Bauer, Shawn M.,Song, Yonghong,Jia, Zhaozhong J.,Mehrotra, Mukund,Huang, Wolin,Xu, Qing,Rose, Jack W.
申请号：
AU2009251863
公开号：
AU2009251863B2
申请日:
2009.04.16
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention is directed to compounds of formula I-II and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as cardiovascular disease, inflammatory disease, autoimmune disease and cell proliferative disorder, thrombosis, allergy, asthma, rheumatoid arthritis, leukemia, or non-Hodgkin's lymphoma.
